this is be cool 8) xylocaine 5 cream Comedian Patrice O’Neal died on Nov. 28 after suffering a stroke in late October, his friends confirm. He was 41. The ‘Opie and Anthony’ radio show, where O’Neal was a frequent guest, confirmed the sad news on Twitter the next day. ‘Yes it’s true that our pal Patrice O’Neal has passed away. The funniest and best thinker I’ve ever known PERIOD. #devastated,’ host Opie tweeted. O’Neal, a long-time fixture in the New York comedy scene, was a diabetic.